|
Books > Science & Mathematics > Biology, life sciences > Cellular biology
|
Buy Now
CCN proteins in health and disease - An overview of the Fifth International Workshop on the CCN family of genes (Paperback, 2010 ed.)
Loot Price: R4,592
Discovery Miles 45 920
|
|
|
CCN proteins in health and disease - An overview of the Fifth International Workshop on the CCN family of genes (Paperback, 2010 ed.)
Expected to ship within 10 - 15 working days
|
The CCN family of genes currently comprises six secreted proteins
(designated CCN16 i.e., Cyr61/CCN1; ctgf/CCN2; Nov/CCN3;
WISP1/CCN4; WISP2/CCN5, and WISP3/CCN6) showing a strikingly
conserved primary structure, with four modules sharing partial
identity with IGF binding proteins, Von Willebrand protein,
thrombospondin and several matricellular proteins and growth
factors. The current view is that CCN proteins modulate signaling
pathways that involve regulatory components of the extracellular
matrix. As such, they likely act as a central hub in the regulation
of mitosis, adhesion, apoptosis, extracellular matrix production,
growth arrest and migration of multiple cell types. The 5th
international workshop on the CCN family of genes, that was held in
Toronto in 2008 brought together scientists from around the world
who have an interest in the biological roles of this emerging
family of proteins. On an educational point of view, the workshop
was a unique place for an efficient diffusion of scientific
information. The present book comprises a series of selected
manuscripts that are based on the original communications that were
presented at the meeting by worldwide leaders in the field of CCN
biology. All major aspects of CCN proteins biology in both normal
and pathological conditions are covered in this volume, from
structure-functions analysis up to the involvement of CCN proteins
in complex physiological functions. In addition to reports that
support the Yin-Yang concept of CCN proteins driving opposite
effects on the same biological process, this book also comprises
several contributions that point to CCN proteins as amenable
targets for therapeutic manipulation of disease processes. Together
with the special issue of Journal of Cell Communication and
Signaling in which authors have extended on the original data
presented at the meeting, the present Proceedings provide an
instant picture and unique update of the state of the art in the
CCN field.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
|
You might also like..
|
Welcome to Loot.co.za!
Sign in / Register |Wishlists & Gift Vouchers |Help | Advanced search
