Cytochrome P450 2E1: Its Role in Disease and Drug Metabolism (Hardcover, 2013 ed.)

The book deals with various clinical aspects of cytochrome P450 2E1 (CYP2E1), which is a potent source for oxidative stress. Oxidative stress is critical for pathogenesis of diseases and CYP2E1 is a major contributor for oxidative stress. Several clinical disorders are associated with changes in regulation of CYP2E1 and the consequent abnormalities, which include alcoholic liver disease, alcoholic pancreatitis, carcinogenesis, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, obesity, hepatitis C virus infection, reproductive organ toxicity, hepatocellular and cholestatic liver cirrhosis, inhibition of bone repair, cross- tolerance in smokers and people treated with nicotine, disorders of the central nervous system, changes in metabolism of protoxicants in the circulatory system and susceptibility to human papillomavirus infection. Hence, CYP2E1 emerges as a new and potent player in aggravating injury and furthering disease complications.

General

Imprint:	Springer
Country of origin:	Netherlands
Series:	Subcellular Biochemistry, 67
Release date:	February 2013
First published:	2013
Editors:	Aparajita Dey
Dimensions:	235 x 155 x 16mm (L x W x T)
Format:	Hardcover
Pages:	256
Edition:	2013 ed.
ISBN-13:	978-9400758803
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
LSN:	9400758804
Barcode:	9789400758803

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