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Books > Medicine > Clinical & internal medicine > Endocrinology
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Control of Metabolic Processes (Hardcover, 1990 ed.)
Loot Price: R5,970
Discovery Miles 59 700
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Control of Metabolic Processes (Hardcover, 1990 ed.)
Series: NATO Science Series A:, 190
Expected to ship within 10 - 15 working days
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THIS BOOK collects together papers given at a NATO Advanced
Research Workshop held at Il Ciocco (Lucca), Italy, from the 9th to
the 15th April, 1989. It sets out to present the current state of
understanding of the principles governing the way fluxes and
concentrations are maintained and controlled in metabolic systems.
Although this is a topic that has held the interest of biochemists
for many years, it is only quite recently that the methods of
analysing the kinetics of multi-enzyme pathways developed over the
past two decades have come to be widely discussed or applied
experimentally. Many biochemists remain sceptical that the new
methods offer a real advance (except in complexity) over the
landmark discoveries of the 1950s and 1960s relating to inhibition
of enzymes at branch-points by the end products of metabolic
pathways, and the interpretation of allosteric effects and
cooperativity. Even those who have become convinced that the
classical ideas provide only the starting point for understanding
metabolic control have been by no means unanimous in their assess
ment of the direction in which one should advance. In this book we
have tried to include all of the current points of view, including
the view that the classical theories tell us all that we need to
know. We have not seen it as our role as editors to paper over the
cracks that exist and to pretend that we can speak to the world
with one voice."
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