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Classical Swine Fever and Related Viral Infections (Paperback, Softcover reprint of the original 1st ed. 1988)
Loot Price: R4,447
Discovery Miles 44 470
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Classical Swine Fever and Related Viral Infections (Paperback, Softcover reprint of the original 1st ed. 1988)
Series: Developments in Veterinary Virology, 5
Expected to ship within 10 - 15 working days
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The history of research on hog cholera (HC)/classical swine fever
(CSF) can be roughly divided into three phases which are
characterized by the methods available at the time for demonstrati
ng the causati ve agent. Phase covered the period before the viral
etiology of HC was discovered by de Schweinitz and Dorset (1904)*.
Thereafter (Phase II) the detection of HC virus (HCV) was
accomplished by laborious, time-consuming and costly pig
inoculation experiments. This explains the extensive search for
methods not only for detection but also for accurate infectivity
titration as well as for applicable serological techniques to solve
urgent problems concerning the pathogenesis, diagnosis,
epidemiology and prophylaxis of HC. It was not before the late
fifties that HC research entered Phase III when fluorescent
antibody techniques offered not only the means for detection and
titration of HCV in porcine cell cultures but also for more
intensive research on hog cholera and its virus. And yet, there are
a number of questions to be answered, e. g. on the genetic and
antigenic relation of HCV to bovine viral diarrhea (BVD) virus.
There are indications that Phase IV of HC research will bear the
stamp of biotechnology. In view of this development it appears
appropriate to give an up-dating and summarizing account of HC/CSF
including comparative aspects of infections caused by structurally
related viruses. The editIon of the present volume would have been
impossible without the cooperation of several known scientists who
instantly agreed when asked for contribution.
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