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Muscle Metabolism During Exercise - Proceedings of a Karolinska Institutet Symposium held in Stockholm, Sweden, September 6-9, 1970 Honorary guest: E Hohwu Christensen (Paperback, 1971 ed.)
Loot Price: R2,749
Discovery Miles 27 490
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Muscle Metabolism During Exercise - Proceedings of a Karolinska Institutet Symposium held in Stockholm, Sweden, September 6-9, 1970 Honorary guest: E Hohwu Christensen (Paperback, 1971 ed.)
Series: Advances in Experimental Medicine and Biology, 11
Expected to ship within 18 - 22 working days
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Howard G. Knuttgen of Biology, Boston University, 2 Cummington
Department Street, Boston, 02215 Massachusetts, USA The
relationship of the formation of lactate acid to skeletal muscle
energy release in exercising humans was first explored by A. V.
Hill and co-workers (2l, 22). The term "oxygen debt" was suggested
by them to describe the excess oxygen consumption of recovery which
they felt was closely related. A combination of their work and the
earlier work of Krogh and Lindhard (35) re sulted at that time in
the belief that a certain amount of energy release during the
transition from rest to exercise was provided by a non-aerobic
source, glycolysis. The resulting accumulation of lactic acid (as
lactate) in the body required an extra con sumption during recovery
for its oxidative removal. Jervell (24) subsequently showed that,
in exercise, the greatest accumulation in blood took place during
the first few minutes. He felt that the blood lactate increase was
due to a shortage of oxygen during the transition period. The
observation was also made for the first time that the increased
level of lac tate due to exercise could be made to fall faster if
mild exercise was employed by the subjects in place of sedentary
recovery. The work of Margaria, Edwards and Dill (40) appeared in
1933. They observed that exercise (treadmill running) could be
carried on at low levels without significant changes in resting
levels of blood lactate.
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