Major strides have been made in the treatment and understanding of
Myelodysplasia.? The United States Food and Drug Administration
(FDA) has approved three new drugs for the treatment of MDS; new
disease genes have been discovered; major insights have been made
into the biology of the disorder; and animal models of MDS have
been developed.? The articles in this issue illustrate the rapid
progress in MDS research, from molecular pathophysiology to
improved therapies.? Insights into the biology of MDS, the
development of model systems to study MDS, and the application of
new technologies with unprecedented power to interrogate the cancer
genome promise to increase the rate of discovery, transforming our
understanding of MDS and leading to improvements in the treatment
this disease.
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