Despite the critical importance of the cerebellum in brain
function, the scientific community still lacks effective treatments
for most cerebellar ataxias. This book provides  a
link between the pathogenesis and therapies of cerebellar ataxias
while also providing a comprehensive assessment of the preclinical
and clinical trials dedicated to cerebellar ataxias over the past
20 years of progress. Â This is the first book fully dedicated
to the trials and therapies of these disorders. It is a truly
authoritative and comprehensive reference, and comes at a time of
major advances in genetic tools and neuroimaging assessments.
 The coverage begins by laying a foundation of the basic
science of the cerebellum and ataxias, proceeds to discuss
biomarkers and the tools of trials, offers guidelines on conducting
trials, Â and then explores the full range of therapeutics and
their trials, including gene therapy and cell transplantation. The
authors are top experts on cerebellar research and the contributing
authors have all made seminal contributions in the field.
General
| Imprint: |
Springer International Publishing AG
|
| Country of origin: |
Switzerland |
| Series: |
Contemporary Clinical Neuroscience |
| Release date: |
June 2023 |
| First published: |
2023 |
| Editors: |
Bing-wen Soong
• Mario Manto
• Alexis Brice
• Stefan M. Pulst
|
| Dimensions: |
235 x 155mm (L x W) |
| Format: |
Hardcover
|
| Pages: |
727 |
| Edition: |
1st ed. 2023 |
| ISBN-13: |
978-3-03-124344-8 |
| Categories: |
Books
Promotions
|
| LSN: |
3-03-124344-7 |
| Barcode: |
9783031243448 |
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