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Teratology - Trends and Applications (Paperback, Softcover reprint of the original 1st ed. 1975)
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Teratology - Trends and Applications (Paperback, Softcover reprint of the original 1st ed. 1975)
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In the fifteen years since the thalidomide disaster teratology has
become a science in its own right, distinct from its progenitors,
experimental embryology and develop mental biology, but bearing
many of the familiar features of both parents. In this growth
period there have been contributions from many different scientific
disciplines as diverse as molecular biology and obstetrics, which
have united in the field of study of congenital malformations.
Scientists in academic departments, government research institutes
and industrial pharmacology have all explored ways of evaluating
the potential of drugs and chem icals to damage the embryo; strict
methods of screening for teratogenicity have be come mandatory in
most parts of the world. Despite a wealth of basic information in
the fields of genetics and embryology, there is little concrete
knowledge of the causal mechanisms of malformation in Man, and even
less concerning the relevance to Man of those laboratory and animal
tests which decide the fate of potentially useful drugs. It is
timely, therefore, that in 1975 a group of young and active sci
entists and clinicians concerned with the broader implications of
teratology should review the past and look to the future of this
emerging speciality. In this volume the editors have blended the
opinions of teratologists; their message presages change in many of
the old and accepted areas of investigative teratology."
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