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Antibiotics and Antibiotic Resistance in the Environment (Hardcover)
Loot Price: R3,233
Discovery Miles 32 330
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Antibiotics and Antibiotic Resistance in the Environment (Hardcover)
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The presence of antibiotics, antibiotic resistance genes, and
antibiotic resistant bacteria in the environment (i.e., outside of
clinical settings, such as antibiotic-treated patients or
antibiotic-impregnated locations, such as hospitals) is a cause of
growing worldwide concern, as it reveals the extensive impact of
antibiotic abuse and other human-related pressures upon microbes.
Also, the potential clinical and environmental impact of the
presence of antibiotic resistance outside the obvious clinical
settings is mostly unknown, but could be unexpectedly large, as
resistance in clinical conditions can be seen as a very small "tip
of the iceberg". The field of detecting and measuring resistance in
the environment has rapidly evolved from mostly anecdotal reports
at the end of the 1990s, to a systematic search of organisms and
genes in a wide variety of settings, from ancient permafrost to
migratory birds. This book will review the available evidence and
hypotheses on where this resistance is coming from and for how long
it has been there; what are the selective and maintenance pressures
involved, and how is resistance spreading; what are the known and
possible traits that are being selected and spread along with
antibiotic resistance ones; what are the laboratory and in-silico
strategies to look into this issue, and their advantages and
disadvantages.
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