Nonclinical Assessment of Abuse Potential for New Pharmaceuticals
offers a complete reference on the current international regulatory
guidelines and details best practice methodology for the three
standard animal models used to evaluate abuse potential: physical
dependence, self-administration and drug discrimination. This book
also includes chapters on alternative models and examples of when
you should use these alternatives. Case histories are provided at
the end of the book to show how the data generated from the animal
models play a pivitol role in the submission package for a new
drug. By incorporating all of this information into one book,
Nonclinical Assessment of Abuse Potential for New Pharmaceuticals
is your single resource for everything you need to know to
understand and implement the assessment of abuse liability.
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