Epidermolysis bullosa (EB) is a heterogenous group of
genodermatoses characterized by the formation of blisters and
erosions on skin and mucous membrans from birth on. The cause are
mutations in the genes of structural proteins of the junction
between epidermis and dermis. This book deals with the treatment of
this skin disease itself and its many extracutaneous complications.
There is no previous book which has been focused on the therapy and
it will be based on evidence-based data derived from the worlds
largest cohort of inherited EB-patients, the American EB Registry.
An important chapter will discuss gene therapy in hereditary EB
which has been recently successfully performed within a localized
skin site on a single EB patient as a proof-of-principle test.
Given its unique collective contents, the monograph will provide
the primary source for clinical informations of this oftentimes
severe multiorgan disease."
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