This monograph brings together our work concerning the
relationships be tween the hypothalamus, pituitary and testis. The
studies span approximate ly a decade of collaborative work. Over
this period our contributions and those of many others have
advanced greatly our understanding of many aspects of male
reproductive biology. This monograph attempts to survey these
developments and to highlight many unresolved issues. It also
provides an opportunity to demonstrate the value of investigations
which relate bio chemical to structural parameters and to
illustrate the importance of animal studies in elucidating
biological principles with clinical applications. The reverse is
also important since the pathophysiology of human disorders of ten
provides insight into hitherto unsuspected basic mechanisms. In any
rapidly expanding field it is difficult to stop revising and
extending a manuscript. It is equally difficult to quote every
reference in the field but we trust that those of significance have
not been omitted. Some of our former students have collaborated
with us as co-authors in producing this monograph. It is equally
important to recognise the contributions of our other former
students and colleagues who have physically participated in the
studies and without whose intellectual contributions a number of
concepts would not have been elucidated. Their work is acknowledged
in the text of the monograph and the extensive list of references."
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