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Bioanalytische Struktur-Funktionsmessungen an Ionenkanalen - Entwicklung optischer Analysemethoden an punktmutierten KcsA und Connexin 26 (German, Paperback, 1. Aufl. 2017) Loot Price: R1,709
Discovery Miles 17 090
Repayment Terms: R160 pm x 12*
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Bioanalytische Struktur-Funktionsmessungen an Ionenkanalen - Entwicklung optischer Analysemethoden an punktmutierten KcsA und...

Bioanalytische Struktur-Funktionsmessungen an Ionenkanalen - Entwicklung optischer Analysemethoden an punktmutierten KcsA und Connexin 26 (German, Paperback, 1. Aufl. 2017)

David Schmidt

Series: BestMasters

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Loot Price R1,709 Discovery Miles 17 090 | Repayment Terms: R160 pm x 12*

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David Schmidt uberpruft, ob der molekulare Schaltmechanismus, der kurzlich in Connexin 26 als rotameres Glu47 mit Fixierung an Lys188 identifiziert wurde, uber Aminosaurenaustauschexperimente auf den Kaliumkanal KcsA ubertragen werden kann. Die Untersuchung struktureller und funktioneller Einflusse der Punktmutationen erfolgte mittels unterschiedlicher Methoden, darunter die Analyse des Schmelzverhaltens mittels SDS-Gel und spektroskopischer Methoden wie der konfokalen Raman-Mikroskopie oder der Microarray-Technologie. Transporteigenschaften von KcsA und Connexin 26 konnten zudem mittels eines Liposom-Transportassays in Abhangigkeit des pH-Wertes sowie dem Vorhandensein von Inhibitoren untersucht werden.

General

Imprint: Springer Spektrum
Country of origin: Germany
Series: BestMasters
Release date: September 2017
First published: 2017
Authors: David Schmidt
Dimensions: 210 x 148 x 4mm (L x W x T)
Format: Paperback
Pages: 66
Edition: 1. Aufl. 2017
ISBN-13: 978-3-658-19144-3
Languages: German
Categories: Books > Science & Mathematics > Biology, life sciences > Molecular biology
Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > General
LSN: 3-658-19144-9
Barcode: 9783658191443

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