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In-Vitro study of Antiplasmodial Activity by of Diospyros melanoxylon (Paperback)
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In-Vitro study of Antiplasmodial Activity by of Diospyros melanoxylon (Paperback)
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Malaria is infectious vector borne parasitic and Plasmodium carried
by the vector mosquitoes, which belong to genus Anopheles. The
first anti-malarial developed later is chloroquine, primaquine,
proquanil, pyrimethamine, metloquine etc. The aim of this study is
to test the in-vitro antiplasmodial effect of extract and different
fractions of Datura innoxia (leaves) and Diospyros melanoxylan
(bark). D.innoxia (leaves) and D.melanoxylon. (barks), are
collected from the lower forest of uttarakhand which is identified
by the local people.The anti-malarial activity of the extract was
discernible as number of parasite in mature schizont form in the
total of 200 parasites. The crude extract (both water and ethanol)
of D. innoxia and D. melanoxylon tested in-vitro had show
antimalarial activity. The result of this preliminary study is very
much encouraging. Natural products are important source of
biologically active compounds and have potential for the
development of novel antimalarial drugs. The eradication of the
disease has been hampered by the emergence and spread of multi drug
resistant malarial parasites, especially P.falciparum strains
resistant to many antimalarial drugs."
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