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Specialized Dementia - A Type of Alzheimer's Disease (Paperback)
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Specialized Dementia - A Type of Alzheimer's Disease (Paperback)
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It was first described by Alois Alzheimer in 1906. At a scientific
meeting in November 1906, German physician Alois Alzheimer
presented the case of "Frau Auguste D.," a 51-year-old woman
brought to see him in 1901 by her family. Auguste had developed
problems with memory, unfounded suspicions that her husband was
unfaithful, and difficulty speaking and understanding what was said
to her. Her symptoms rapidly grew worse, and within a few years she
was bedridden. She died in spring 1906.Dr. Alzheimer had never
before seen anyone like Auguste D., and he gained the family's
permission to perform an autopsy. In Auguste's brain, he saw
dramatic shrinkage, especially of the cortex, the outer layer
involved in memory, thinking, judgment and speech. Under the
microscope, he also saw widespread fatty deposits in small blood
vessels, dead and dying brain cells, and abnormal deposits in and
around cells. The condition entered the medical literature in 1907,
when Alzheimer published his observations about Auguste D. In 1910,
Emil Kraepelin, a psychiatrist noted for his work in naming and
classifying brain disorders, proposed that the disease be named
after Alzheimer.
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