Oral drug delivery is the most widely utilized route of
administration among the entire route that has been explored for
the systemic delivery of drug via various pharmaceutical products
of different dosage form. The conventional tablet seems to be most
popular because of its ease of transportation and low manufacturing
cost as compare to others but poor patient compliance with whom
experienced swallowing difficulties. In response to this mouth
dissolving drug delivery system (MDDs) were developed as an
alternative to tablet, capsule and syrup. A variety of MDDs like
Mouth dissolving tablets (MDTs) and Mouth dissolving films (MDFs)
were commercialized. This book describes the design and development
of sildenafil citrate mouth dissolving film. As sildenafil citrate
is a widely utilized drug for erectile dysfunction. This produced
mouth dissolving film prepared by newer polymer Kollicoat protect
and showed the good alternative for the other mouth dissolving film
former, specially HPMC. Stevioside a natural sweetener used and
showed the potency to mask the bitter taste of sildenafil citrate.
Hence, MDF of sildenafil citrate provide good alternate to other
available dosage form.
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