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Trends in Human Hair Growth and Alopecia Research (Paperback, Softcover reprint of the original 1st ed. 1989)
Loot Price: R1,485
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Trends in Human Hair Growth and Alopecia Research (Paperback, Softcover reprint of the original 1st ed. 1989)
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It is now thirty years since William Montagna and Richard Ellis
edited 'The Biology of Hair Growth". In his introduction, Stephen
Rothman, of the University of Chicago, USA and one of the driving
forces behind research on skin at the time, wrote: 'The pilary
system is a perfect micr9cosmic structure. In this microcos- mos we
find birth, development, ageing and death, activity and rest, color
for- mation and decolorification, greasiness and dryness, infection
and sterilization, hypertrophy and atrophy, Qenign tumours and
malignant ones. " He foresaw the human pilary system as a model for
the study of a multitude of human diseases including ageing and
cancer. It was not, how- ever, until the seventies that the
development of micro-biochemical tech- niques indeed allowed the
use of the human hair follicle as a convenient biopsy tissue for
Biomedical Research in general. Measurement of enzyme activities,
and important co-factors, and culturing of cells from single
follicles all became possible. In the eighties dermal papilla cells
were grown in cul- ture and this opened the way to study hair
differentiation in vitro. Studying hair differentiation is, in
fact, studying growth regulation and it is this aspect that by far
transcends the importance of studying hair growth itself. Let us
not forget that metastatic prostate cancer is treated with the same
drug -cyproterone acetate -that is used for the treatment of
alopecia and hirsutism in women.
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