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Books > Business & Economics > Business & management > Management & management techniques > Management decision making
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Theoretical and Mathematical Foundations of Human Health Risk Analysis - Biophysical Theory of Environmental Health Science (Hardcover, 1997 ed.)
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Theoretical and Mathematical Foundations of Human Health Risk Analysis - Biophysical Theory of Environmental Health Science (Hardcover, 1997 ed.)
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Scientists and regulators have struggled to define the role of
theory, experiments, models and common sense in risk analysis. This
situation has been made worse by the isolation of theory from
modeling, of experimentation from theory, and of practical action
from basic science. This book arises from efforts at regulatory
agencies and industries to bring more science into health risk
analysis so that society may better use limited resources to
improve public health. This book covers: the characterization of
exposure to pollutants and other sources of risk; the movement of
pollutants into the body via inhalation; ingestion, dermal
absorption, and exposures to radiation; the movement of a pollutant
as it cascades through the tissues and organs of the body; and the
development of principles and models for dose-response modeling.
The book shows how an understanding of the biological, chemical,
and physical properties of the environment and of the human body
can guide the selection of mathematical models, and how these
models can aid in estimating risks. Included in the book are models
covering the full range of topics in human health risk analysis:
exposure assessment, rates of intake, deposition and uptake by
organs, absorption across membranes, biokinetics, dosimetry, and
dose-response. The reader will gain from the book a better
understanding of how environmental health science, as applied in
risk analysis, can be used to create a more rational basis for the
improvement of public health.
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