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Horizons in World Cardiovascular Research - Volume 15 (Hardcover)
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Horizons in World Cardiovascular Research - Volume 15 (Hardcover)
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In this compilation, the authors present and discuss various
aspects of arrhythmias in endurance competitive and leisure-time
sportsmen including master athletes based on their extensive
experience and international literature. The value of heart rate
monitors for evaluating exercise intensity and for diagnosis of
arrhythmias is discussed and standard procedure for dealing with
suspected arrhythmias useful both for athletes, their coaches or
doctors is proposed. Next, the authors focus on recent literature
data related to the role of endothelial nitric oxide and inducible
nitric oxide in physiological and pathophysiological conditions.
Nitric oxide is a free radical which, in reactions with various
molecules, causes multiple biological effects. It is exceptionally
regulated and extends to almost every cell type and function within
circulation. Extracranial carotid artery stenosis is a major cause
of stroke and is treated with either carotid endarterectomy (CEA)
or percutaneous transluminal angioplasty (PTA) and carotid artery
stenting (CAS). In this collection, several types of imaging study
have been used to identify complications related to in-stent
restenosis, including Doppler ultrasound, computed tomography
angiography, digital subtraction angiography, magnetic resonance
angiography, intravascular ultrasound, and optical coherence
tomography. The authors go on to discuss some recent randomized
studies that compared different d rug-eluting balloon catheters
(DEB) with drug-eluting stents (DES) used to treat BMS- in-stent
restenosis or DES- in-stent restenosis, and the long-term clinical
results of those studies. Evidence from controlled clinical studies
has suggested that DES and drug-eluting balloon catheters (DEB)
provide the best clinical and angiographic results in the treatment
of ISR. Following this, the dynamics of the conformation changes in
the subdomains of the NC1 hexamer under the influence of sound
frequencies distressing them was studied in gelatin (film) and
collagen (cardiac aorta/veins endothelium) obtained from pork,
using the gravitation mass spectroscopy method (GMS). Continuing,
most coronary events are caused by significant stenoses or
vulnerable plaques. Recent studies have shown that significant
stenoses and vulnerable plaques often coexist. The basic concept
that underlies these entities is increased plaque volume.
Additionally, recent evidence shows that coronary calcium score and
fractional flow reserve are the most accurate methods to assess
increased plaque volume, and therefore, have high prognostic value.
The main goal of the subsequent study is the application of an
immunohistochemistry technique in order to diagnose myocardial
ischemia in early stages with a better confidence rate. Sudden
cardiac death cases were selected and their findings were
qualitatively and quantitatively assessed. The study focuses on the
evolution and location of fibronectin in the ischemic
cardiomyocytes during process of infarction and remodeling of
cardiac scars. Lastly, the authors investigate the incidence of
very late in-stent restenosis and risk factors for very late target
lesion revascularization (TLR) in patients with sirolimus-eluting
stent (SES). Very late SES-TLR was associated with history of
hemodialysis and previous PCI with SES for ISR lesion.
General
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