There are several types of damage that can be found in the male
gamete. Genetic damage in spermatozoa can originate during
spermatogenesis, or it can originate during transit in both male
and female genital tracts. Damage can also be due to ageing,
environmental or iatrogenic conditions, as well as to the protocols
to cryopreserve and to select spermatozoa in assisted reproduction
techniques. The purpose of this book is to provide a comprehensive
resource for all possible DNA damages in sperm, the relation to
fertility and infertility, and possible transgenerational heritable
effects.
General
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