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Endocannabinoids - The Brain and Body's Marijuana and Beyond (Hardcover)
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Endocannabinoids - The Brain and Body's Marijuana and Beyond (Hardcover)
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Over the past decade, there have been major advances in
understanding the mechanisms whereby marijuana interacts with the
brain in producing psychoactive and potentially therapeutic
effects. The discovery of specific gene coding for cannabinoid
receptors activated by smoking marijuana, and the finding of
endogenous cannabinoids, which also activate the receptors, have
transformed cannabinoid research into mainstream science with
significant implications in human health and disease
Endocannabinoids: The Brain and Body's Marijuana and Beyond
documentsadvances in the discovery and functioning of naturally
occurring marijuana-like substances in human biology. It explores
recent findings that point to the existence of an endocannabinoid
physiological control system (EPCS) that directly impacts human
development, health, and disease. While cannabinoid effects on the
brain have received the greatest attention throughout the
literature, this work looks at research on the endogenous
cannabinoid system's association across all of human physiology,
including the immune, endocrine, and reproductive systems. With
thoroughly researched and exceptionally insightful contributions
from more than three-dozen top-flight researchers representing a
cross-section of disciplines from molecular biology, genetics, and
neurology to gynecology, physiology, and pharmacology, this work
explores a range of topics as wide as the human body is complex.
These topics include the EPCS's relation to cell development and
regulation, CNS function, immune function modulation, reproduction,
and digestion, as well as its function in mental illness,
neurodegenerative diseases, and cancer. The final section in the
book considers the significance of endogenous cannabinoids found in
some of the simplest multicellular organisms in the animal kingdom,
as well as in mammalian cells at the earliest stages of
development, all of which suggests that they play a fundamental
role in human biology.
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