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Chirurgisches Forum'80 - Fur Experimentelle Und Klinische Forschung, 97. Kongress Der Deutchen Gesellschaft Fur Chirurgie, Munchen, 14. Bis 17. Mai 1980 (English, German, Paperback)
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Chirurgisches Forum'80 - Fur Experimentelle Und Klinische Forschung, 97. Kongress Der Deutchen Gesellschaft Fur Chirurgie, Munchen, 14. Bis 17. Mai 1980 (English, German, Paperback)
Series: Deutsche Gesellschaft fur Chirurgie, 80
Expected to ship within 10 - 15 working days
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22 polytraumatisierte und septische Patienten einer Intensiv-
station wurden im Rahmen einer Doppelblindstudie mit Pirenzepin
bzw. Placebo behandelt. Alle Patienten wurden wahrend des Beob-
achtungszeitraumes in 14 Tagen dreimal endoskopiert. Ohne Pro-
phylaxe waren 100% StreB-Lasionen zu beobachten, 60% wiesen Blu-
tungen auf. Eine prophylaktische, intravenose Pirenzepin-Gabe hatte
einen eindeutig protektiven Effekt im Hinblick auf die
StreB-Blutung, Anzahl und Schweregrad der StreB-Lasionen. Summary
Twenty-two severely ill patients with multinle injuries and sepsis
were treated with IV pirenzepin or placebo 3 x 10 mg per day in the
frame of the double-blind study. All the patients were examined
three times with endoscopy during the 14-day ob- servation period.
In 100% of cases without prophylactic treat- ment, stress lesions
were observed, 60% of these cases had bleeding. A prophylactic IV
pirenzepin application had an un- mistakable protective effect
regarding the stress bleeding, number and degree of stress lesions.
Literatur 1. BRODIE, D.A.: Experimental peptic ulcer.
Gastroenterology 55, 125-134 (1968) 2. EINIG, D.: Ein neuer
Sekretionshemmer. Ergebnisse einer Wir- kungs- und
Vertraglichkeitsprufung mit Gastrozepin. Therapie- woche
27,1630-1638 (1977) 3. HASTINGS, P.R., SKILLMAN, J.J., BUSHNELL,
L.J. et al.: Antacid titration in the prevention of acute
gastrointestinal bleeding: a controlled randomized trial in 100
critically ill patients.
General
Imprint: |
Springer-Verlag
|
Country of origin: |
Germany |
Series: |
Deutsche Gesellschaft fur Chirurgie, 80 |
Release date: |
May 1980 |
First published: |
1980 |
Editorial coordinators: |
F. Linder
• H.D. Roher
• U Mittmann
|
Editors: |
H Junghanns
|
Dimensions: |
244 x 170 x 19mm (L x W x T) |
Format: |
Paperback
|
Pages: |
336 |
ISBN-13: |
978-3-540-10035-5 |
Languages: |
English
•
German
|
Categories: |
Books >
Medicine >
General issues >
General
|
LSN: |
3-540-10035-0 |
Barcode: |
9783540100355 |
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