Nonsense Mutation Correction in Human Diseases - An Approach for Targeted Medicine (Paperback)

Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine provides an introduction on genetic diseases, discusses the prevalence of nonsense mutations, the consequences of a nonsense mutation for the expression of the mutant gene, and the presentation of the nonsense-mediated mRNA decay (NMD). It presents the mechanism of action and rationale associated with each strategy to correct nonsense mutations with the results of clinical trials to further support this basis. In addition, the book shows how it may be possible to combine several of these strategies to ultimately improve the efficiency of correction, also suggesting the future goals and objectives to improve treatment modalities in this evolving sphere of personalized medicine.

General

Imprint:	Academic Press Inc
Country of origin:	United States
Release date:	April 2016
Authors:	Fabrice Lejeune • Hana Benhabiles • Jieshuang Jia
Dimensions:	229 x 152 x 14mm (L x W x T)
Format:	Paperback
Pages:	190
ISBN-13:	978-0-12-804468-1
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Promotions
LSN:	0-12-804468-3
Barcode:	9780128044681

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