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Clinical Aspects of Blood Viscosity and Cell Deformability (Paperback, Softcover reprint of the original 1st ed. 1981)
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Clinical Aspects of Blood Viscosity and Cell Deformability (Paperback, Softcover reprint of the original 1st ed. 1981)
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After many years of relative neglect, the importance of study of
factors governing blood flow has at last achieved recognition; in
this volume are documented many of the techniques, and the basic
scientific and clinical observations, which have helped to open up
understanding of this highly important aspect of human physiology
and pathology in recent years. The text is logically divided into
five sections beginning with blood cell deformability, then moving
on to theoretical consideration of blood rheology, followed by
accounts of the interrelationships between rheology, blood flow and
vascular occlusion. The final two sections deal with blood rheology
in clinical practice and therapeutic aspects of the study of blood
flow. As regards blood cell deformability (Section A), the basic
problem is set out by Kiesewetter and colleagues in the first
paragraph of chapter 1 (p. 3), in which they point out that whereas
human erythrocytes at rest have a diameter of approxi mately 7. 5
/-tm, nutritive capillaries have diameters ranging from 3-5 /-tm,
and chapters in section A give an account of the ways in which the
red cell can undergo deformation to permit capillary perfusion and
the maintenance of the microcirculation."
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