In a variety of cardiac diseases the influence of heart rate on
cardiac function is altered and both heart rate and heart rate
variability are of great relevance for the prognosis of cardiac
patients. This book provides a summary of the current knowledge on
the influence of heart rate on myocardial function and hemodynamics
in non-failing and failing animal and human hearts. The subcellular
and molecular alterations underlying the altered heart rate
response in heart failure are discussed in detail. In addition,
studies related to the impact of heart rate and heart rate
variability on arrhythmogenesis and prognosis in patients with
cardiac diseases are critically reviewed. Finally, the relevance of
heart rate control by therapeutic interventions is also discussed.
The book contains 19 different chapters written by well-known
experts in this novel and clinically important field.
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