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Pharmacology of the Eye (Paperback, Softcover reprint of the original 1st ed. 1984)
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Pharmacology of the Eye (Paperback, Softcover reprint of the original 1st ed. 1984)
Series: Handbook of Experimental Pharmacology, 69
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Roots of the theory and practice of ocular pharmacology may be
traced to the ancient Mesopotamian code of Hammurabi and then to
several papyri reflecting the clinical interests of the Egyptians.
The evolution of its art and science was irregularly paced until
the nineteenth century when Kohler, in 1884, proved the anesthetic
effect of cocaine on the cornea, and when Fraser, Laquer,
Schmiedeberg, Meyer, and others studied the pharmacology of the
autonomic nervous system by way of observations of the pupil.
Advances in the past few decades have been nothing short of
explosive. How can the student, physician, or basic research
scientist stay in touch with these electrifying studies? To help
with the answer to this question, the authors set as their goal the
development of increased understanding so that the student,
research scientist, and ophthalmologist can cope with the latest
discoveries. The authors want to narrow what appears to be an
ever-increasing gap between basic science and ophthalmology. The
basic aspects of pharmacology have been presented in light of the
natural physiology. In this regard, while distinctions among
endogenous mechanisms, drug effects, and the pathogenesis of
disease are to be separately recognized, appreciation must be given
to the concept that both the desirable and unwanted manifestations
or functions caused by either disease or drugs must very often
represent a quantitative change in normal metabolic pathways.
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