This volume, the fourth in the series "The Prostagiandin System,"
contains most of the presentations at the International School of
Pharmacology on "Drugs Effecting Leukotrienes and other Eicosanoid
pathways" held in Erice, Sicily, at the "Ettore Majorana Center" on
9-20 September 1984. The discovery of a new class of biologically
active compounds is always exciting even if at the present time
knowledge is advancing very rapidly; this is particu1arly true for
the eicosanoids. Evidence for a pivotal role of arachidonic acid as
a precursor of mediators and modulators of various cell functions
is now weil established. This broad knowledge has stimulated the
search for drugs capable of interfering with the eicosanoid system
and since the discovery of the mechanism of action of Aspirin, new
drugs have become available in order to act more specifica11y not
only at the level of different enzymes involved in arachidonic acid
conversion but also more selectively at the receptor si tes where
the acti ve metaboli tes are effecti ve. In addition to this,
several stable synthetic derivatives of endogenous unstable
prostanoids mimicking their functions in a variety of
physiopatho19gical processes are also of potential therapeutic
interest. This volume will certainly help scientists and students
wi th different interests related to those diseases that stern from
arachidonic acid metabolites interactions in hypersensitivity
phenomena and in host defence mechanisms.
General
Imprint: |
Springer-Verlag New York
|
Country of origin: |
United States |
Series: |
NATO Science Series A:, 95 |
Release date: |
May 2012 |
First published: |
1985 |
Editors: |
G. Velo
|
Dimensions: |
254 x 178 x 21mm (L x W x T) |
Format: |
Paperback
|
Pages: |
394 |
Edition: |
Softcover reprint of the original 1st ed. 1985 |
ISBN-13: |
978-1-4684-7843-3 |
Categories: |
Books >
Medicine >
Other branches of medicine >
Pharmacology >
General
|
LSN: |
1-4684-7843-5 |
Barcode: |
9781468478433 |
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