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Mouse Models for Drug Discovery - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2010)
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Mouse Models for Drug Discovery - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2010)
Series: Methods in Molecular Biology, 602
Expected to ship within 10 - 15 working days
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As the drug discovery process shifts more and more toward
specifically targeting pathways and molecules, model systems
continue to increase in importance, and the mouse, with its
versatility, ease of use, and remarkable similarity to the human
genome, has clearly risen to the forefront of animal model studies.
In Mouse Models for Drug Discovery: Methods and Protocols, experts
in the field present some background for those less familiar with
mice as experimental model platforms as well as a collection of
techniques involving general methods as well as specific disease
topics such as type 1 and 2 diabetes, cardiovascular disease,
arthritis, skin disorders, cancer, the use of behavioral models for
depression and anxiety, neurodegenerative diseases, neuromuscular
diseases, and infectious diseases. Written in the highly successful
Methods in Molecular Biology (TM) series format, chapters include
introductions to their respective topics, lists of the necessary
materials and reagents, step-by-step, readily reproducible
laboratory protocols, and notes on troubleshooting and avoiding
known pitfalls. Authoritative and easy-to-use, Mouse Models for
Drug Discovery: Methods and Protocols will stimulate those not
familiar with the power of the mouse and its potential for the drug
discovery process, and it will encourage the development of new
models and new ways to utilize existing models in order to further
the use of this dynamic animal in this vital field.
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