The present book provides a state-of-the-art overview of the
adrenal gland pathophysiology. It covers both up-to-date basic and
clinical notions on adrenal glands. Amidst the molecular aspects,
discussed by leading scientists in the field, there are ER stress,
microRNA, hormone biosynthesis, and interactions with other organs.
Clinical insights for students and physicians are also provided,
from the imaging to the therapeutic management of common disorders
of the gland, including adrenal failure, hyperaldosteronism,
Cushing's syndrome, neurologic disease, and cancer both in adults
and pediatric patients. As mentioned above, chapter contributions
are made by worldwide renowned experts, scientists and physicians,
working in prestigious hospitals and universities including Brown,
Oxford, Case Western Reserve University, Cleveland Clinic, Chinese
University of Honk Kong, University of Tennessee, Indiana
University School of Medicine, Monash Health in Clayton, Australia,
University of Calgary, Northern Ontario School of Medicine and
Laurentian University, Medical University of Gdansk, Universite
Pierre et Marie Curie in Paris, France, University of Minho, Braga,
Portugal, St. Vincent's University Hospital in Dublin, Universities
of Londrina, Alfenas, Sao Paulo, and Rio de Janeiro, Brazil.
Throughout these chapters, the authors spotlight future avenues for
research in basic pathophysiology and in therapy/prevention, in
addition to thorough overviews of the current literature pertaining
to the adrenal gland and its functional roles. The book also
includes several color photographs, schemes and diagrams of
molecular relationships, and tables that support and complement the
text. The comprehensive and systematic overview provided within
this book is expected to assist the reader in comprehending the
importance of taking into account the functional roles of the
adrenal gland and also to address questions and unresolved issues
regarding the treatment of its disorders. Finally, the editor would
like to express his sincere appreciation to all the contributors
for their dedicated collaboration in this project. He would also
like to thank Ms. Carra Feagaiga for her patient support. He
sincerely hopes this book will enable readers to connect basic
research principles with up-to-date clinical knowledge, thereby
encouraging future discoveries and developments of new therapeutic
strategies to treat disorders of the adrenal gland.
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