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Formulation And Evaluation Of Nanosuspension Of Anti-Cancer Drug (Paperback)
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Formulation And Evaluation Of Nanosuspension Of Anti-Cancer Drug (Paperback)
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Paclitaxel is a anti-cancer agent, mainly used in the cases of
Breast, Cervical and Lung cancers. To increasing bio availability
and Extending circulation time (EPR effect) of the drug in blood
thereby increasing its half-life. Paclitaxel nanosuspension was
prepared by high pressure homogenization method using different
concentration of Human Serum Albumin (HSA). A total of 9
formulations of nanosuspensions were prepared by varying
concentration of Human Serum Albumin (HSA) and by keeping the drug
concentration as constant. All the formulations were developed
successfully and evaluation tests have been performed. Human Serum
Albumin in different concentrations like 12.5%, 20% and 30% showed
very good results
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