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Biochips as Pathways to Drug Discovery (Hardcover)
Loot Price: R1,812
Discovery Miles 18 120
You Save: R2,894
(61%)
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Biochips as Pathways to Drug Discovery (Hardcover)
Series: Drug Discovery Series
Expected to ship within 12 - 17 working days
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Donate to Against Period Poverty
Total price: R1,832
Discovery Miles: 18 320
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In the fiercely competitive pharmaceutical marketplace, your
organization cannot afford to spend excess dollars developing drugs
that will fail to get FDA approval or have profoundly poor
characteristics. Biochips as Pathways to Drug Discovery takes a
comprehensive look at how the industry faces these challenges,
using new technologies such as biochips to reduce the cost of drug
discovery and improve drug safety. The book explores the tools and
skills required at each step of the discovery process when using
biochips to determine biological outcomes. The authors provide an
in-depth review of the clinical and pharmacogenomic relevance of
biochips, ChIP-chip assays, and high-throughput approaches. They
discuss how biochips are used to develop biomarkers in the drug
discovery process, primarily for gene expression profiling and
Single Nucleotide Polymorphism (SNP) analysis. The book includes
coverage of experimental theory, quality control, clinical
laboratory sampling considerations, database concepts, industrial
laboratory design, and the analysis of the resultant large data
sets. It discusses the application of biochips to the study of
malaria, toxicogenomics, and SNPs, as well as intellectual property
and market overviews. The book concludes with a comprehensive
overview of how these chips are employed from early target
discovery through preclinical toxicology and on through to
pharmacogenomic and proof of concept studies in humans. Written in
an easily accessible style, the breadth of coverage introduces the
subject to those new to the field, while the depth of coverage
forms a foundation for future work. The book gives you the
knowledge required to leverage the technology into bona fide
discoveries. Daniel E. Levy, editor of the Drug Discovery Series,
is the founder of DEL BioPharma, a consulting service for drug
discovery programs. He also maintains a blog that explores organic
chemistry.
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