A current survey and synthesis of the most important findings in
our understanding of the neurobiological mechanisms of addiction is
detailed in our Neurobiology of Addiction series, each volume
addressing a specific area of addiction. Opioids, Volume 4 in the
series, explores the molecular, cellular and systems in the brain
responsible for opioid addiction using the heuristic three-stage
cycle framework of binge/intoxication, withdrawal/negative affect,
and preoccupation/anticipation.
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