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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Thyroid and Heart Failure - From Pathophysiology to Clinics (Paperback, Softcover reprint of hardcover 1st ed. 2009)
Loot Price: R3,080
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Thyroid and Heart Failure - From Pathophysiology to Clinics (Paperback, Softcover reprint of hardcover 1st ed. 2009)
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Both thyroid dysfunction and heart failure show a high prevalence
in the adult population. Frequently, in clinical practice, a
multidisciplinary approach is useful to optimize the management of
patients with these conditions. Although there is no doubt
regarding the close link between cardiovascular pathophysiology and
thyroid homeostasis, our understanding of this association is far
from being exhaustive. Thyroid hormone regulates the expression of
cardiac-specific functional contractile and structural proteins and
plays a pivotal role in modulating both diastolic and systolic
function as well as peripheral vascular resistance. The close
relationship between thyroid and heart dysfunction is strongly
supported by recent evidence demonstrating that an altered thyroid
profile is a negative prognostic predictor in patients with heart
failure. The treatment of chronic heart failure, especially in
advanced stages of the disease, continues to be an open and
challenging field. The potential of novel thyroid hormone therapies
that address the molecular biology of thyroid dysfunction and heart
failure thus represents an attractive area of multidisciplinary
scientific interest. This book is a readable, integrated, and
highly up to date presentation of the clinical, pathophysiological,
and basic science aspects of thyroid-heart failure interactions. It
addresses a complex subject in an approach that targets a large
audience of readers.
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