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Books > Medicine > Pre-clinical medicine: basic sciences > Human reproduction, growth & development > Reproductive medicine
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Spermatogenesis - Molecular Mechanisms, Regulation & Biological Perspectives (Hardcover)
Loot Price: R3,209
Discovery Miles 32 090
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Spermatogenesis - Molecular Mechanisms, Regulation & Biological Perspectives (Hardcover)
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Spermatogenesis is a tightly regulated cellular renovation and
differentiation process. It consists of self-renewal and
differentiation of spermatogonial stem cells (SSCs), spermatocytic
meiosis and spermiogenesis; each of these processes is essential to
the continuous, successful production of male gametes. During
spermiogenesis, haploid spermatids undergo extensive cellular,
molecular and morphological changes, including acrosome biogenesis,
flagellum development, cytoplasmic reorganization and chromatin
condensation. These changes ultimately result in mature spermatozoa
with an acrosome-covered head and motile tail. In this book,
Chapter One summarizes the progress that has been made in
understanding the molecular mechanisms underlying acrosome
biogenesis, and the authors discuss the potential directions of
future investigations of this process. Chapter Two briefly
addresses the basics of spermatogenesis and the synthesis of
ncRNAs, and then the authors discuss the recent progress in
understanding of the functions of miRNAs, endo-siRNAs, piRNAs and
lncRNAs in the regulation of spermatogenesis. Chapter Three
provides a review of the current literature on testicular
immunoregulation and its underlying mechanisms, along with its
effect on testicular functions.
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