Gamma-hydroxybutyrate (GHB) has come a long way since early
experiments in animals where it was found to induce a sleep-like
state and from its use in general anaesthesia in human subjects. It
has been found to be a naturally-occurring compound in the brain, a
metabolite of GABA, the emerging ubiquitous inhibitory
neurotransmitter. This has opened up a completely new line of
research in an effort to establish a function for GHB.
Gamma-Hydroxybutyrate: Pharmacological and Functional Aspects has
brought together the combined expertise of many of the leading
authorities on the biochemistry, physiology and pharmacology of GHB
in the central nervous system. Each chapter is an in-depth review
of the field and the book itself will appeal to all neurobiologists
interested in neurotransmitter mechanisms, as well as to clinicians
and other health-care workers interested in this fascinating
chemical.
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