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Foundations of the Neuron Doctrine (Hardcover, New)
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Foundations of the Neuron Doctrine (Hardcover, New)
Series: History of Neuroscience, 6
Expected to ship within 12 - 17 working days
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For a century, the neuron doctrine has been the basis for our
concepts of nervous organization and brain function. Formulated in
1891 by Wilhelm Waldeyer, it stated that the cell theory applies to
the nervous system. Santiago Ramon y Cajal, Spain's greatest
scientist, was its main architect; his main tool was a capricious
nerve cell stain discovered by Camillo Golgi. This book reviews the
original papers on which the neuron doctrine was based, showing
that the evidence came from a much wider base of contributions than
is generally realized, including such diverse and brilliant
personalities as Albrecht Kolliker, Sigmund Freud, Wilhelm His,
August Forel, Fritdjof Nansen and Gustav Retzius. Furthermore, many
questions about terminology of the parts of the neuron and about
the organization of neurons into reflex pathways and networks were
raised and debated, questions that remain relevant to this day.
Electron microscopical studies in the 1950s appeared to confirm the
classical doctrine, but subsequent studies have revealed
complexities that were not anticipated. This book reviews these new
studies against the background of the classical work, and suggests
some new directions for revising our concept of the neuron as a
basis for the functional organization of the nervous system.
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