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Phytochemical and Antiulcer Activity of Careya Arborea Roxb. (Paperback)
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Phytochemical and Antiulcer Activity of Careya Arborea Roxb. (Paperback)
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Padmaka is an important drug used as one of the ingredients in many
Ayurvedic preparations. The accepted source of this drug is the
heart-wood or some times the stem of Prunus cerasoides D. Don of
family Rosaceae. The south Indian market sample of Padmaka is
identified as the flowers of Careya arborea Roxb of family
Lecythidaceae. The present study was undertaken to evaluate
pharmacognostical characters, phytochemical analysis and
pharmacological studies (antiulcer activity) on stem bark of C.
arborea Roxb. To carry out this study, the drug material was
collected from surroundings of Papanasam forests vicinity of
Tirunelveli district, Tamil Nadu. For antiulcer activity, three
models such as ethanol induced, cold stress induced and pyloric
ligation model were adopted. To the animals having ulcer, the
alcohol and aqueous extract was given orally and observed for
reduction in ulcer index, volume of gastric juice and total
acidity. Both extracts offered protection against ulcer and the
effects were found to be dose dependent. The antiulcer activity was
found to be statistically significant when compared with the
control group.
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