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Caliciviruses - Molecular and Cellular Virology (Hardcover)
Loot Price: R5,518
Discovery Miles 55 180
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Caliciviruses - Molecular and Cellular Virology (Hardcover)
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Caliciviruses are positive-sense, single stranded RNA viruses
containing four recognized genera: Norovirus, Sapovirus, Lagovirus,
and Vesivirus. They are ubiquitous in the environment and are a
major cause of disease in humans as well as many animals. Examples
include Norwalk virus - a norovirus, thought to be responsible for
roughly 90% of epidemic, non-bacterial outbreaks of gastroenteritis
in humans around the world. The lack of a suitable cell culture
system for human caliciviruses has limited studies in previous
decades, however the recent application of modern genomic
technologies has revolutionized the field, leading to an explosion
in calicivirus publications. In this book, a panel of experts
distil the most important up-to-date research findings in their
respective calicivirus field of study, producing timely and
comprehensive reviews. Each chapter gives the reader a brief
introduction to the topic, followed by a descriptive discussion of
the past and present research areas. Topics include: norovirus
epidemiology * calicivirus contamination of the environment *
genome organization and recombination, proteolytic cleavage, and
viral proteins * viral protein structures * virus-host interactions
* calicivirus reverse genetics and replicon systems * feline
calicivirus * swine calicivirus * murine norovirus pathogenesis and
immunity * murine norovirus translation, replication, and reverse
genetics * and lagoviruses. This book will be essential reading for
all virologists working on caliciviruses and related viruses and is
recommended for all virology, immunology, and molecular biology
laboratories.
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