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Risk Assessment for Human Metal Exposures - Mode of Action and Kinetic Approaches (Paperback)
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Risk Assessment for Human Metal Exposures - Mode of Action and Kinetic Approaches (Paperback)
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Risk Assessment for Human Metal Exposures: Mode of Action and
Kinetic Approaches examines the current principles of risk
assessment in human metal exposures, with a focus on Mode of
Action(MOA), Toxicokinetic and Toxicodynamic (TKTD) considerations,
and computer models. Derived from the highly respected Handbook on
the Toxicology of Metals, Fourth Edition (2014), the book
summarizes principles and methods and provides examples of how MOA
-TKTD can be used. In addition, it presents tactics on how
information generated by such methods can be confirmed by
epidemiological data. Furthermore, it demonstrates how
epidemiological data can be confirmed and evaluated by the examined
models and considerations. This resource uniquely integrates
several important topics, such as risk assessment,
characterization, management and communication-the classic risk
assessment paradigm-with mode of action, TKTD, and epidemiology,
all topics related to human exposure. Written by pioneers in the
field, this book is an essential reference for researchers,
students and technicians in toxicology and risk assessment.
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