The morphological behaviour of leucocytes* leaving the blood has
been studied for more than a hundred years and can be described in
some detail, but the mechanisms involved are for the most part
still unclear. Following an inflammatory stimulus, dy- namic
changes occur in small blood vessels near the inflamed site and are
followed by margination of leucocytes and by their adherence to the
endovascular surface of endo- out of the vessel in the gaps between
endothelial thelial cells. The leucocytes migrate cells and move
towards the noxious stimulus, directed presumably by chemotactic
gra- dients. Having reached the gradient source, they may engage in
phagocytosis, killing and digestion of micro-organisms or of
damaged tissue. In this review, we deal with the adhesive
properties of leucocytes, which have US1,l;ll- ly been measured in
vitro, and with their possible relevance to the leucocyte-endo- We
also deal with the locomotion of leucocytes, its machinery thelial
cell interaction.
General
Imprint: |
Springer-Verlag
|
Country of origin: |
Germany |
Series: |
Current Topics in Pathology, 68 |
Release date: |
December 2011 |
First published: |
1979 |
Editors: |
H Z Movat
|
Dimensions: |
244 x 170 x 16mm (L x W x T) |
Format: |
Paperback
|
Pages: |
298 |
Edition: |
Softcover reprint of the original 1st ed. 1979 |
ISBN-13: |
978-3-642-67313-9 |
Categories: |
Books >
Medicine >
Clinical & internal medicine >
Dermatology
|
LSN: |
3-642-67313-9 |
Barcode: |
9783642673139 |
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