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Membrane Transport and Renal Physiology (Paperback, Softcover reprint of the original 1st ed. 2002)
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Membrane Transport and Renal Physiology (Paperback, Softcover reprint of the original 1st ed. 2002)
Series: The IMA Volumes in Mathematics and its Applications, 129
Expected to ship within 10 - 15 working days
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The papers in this volume arose out of the workshop Membrane
Transport and Renal Physiology, which was conducted as part of the
IMA 1998-1999 program year, Mathematics in Biology. The workshop
brought together physiologists, biophysicists, and applied
mathematicians who share a common interest in solute and water
transport in biological systems, especially in the integrated
function of the kidney. Solute and water transport through cells
involves fluxes across two cell membranes, usually via specialized
proteins that are integral membrane components. By means of
mathematical representations, transport fluxes can be related to
transmembrane solute concentrations and electrochemical driving
forces. At the next level of functional integration, these
representations can serve as key components for models of renal
transcellular transport. Ultimately, simulations can be developed
for transport-dependent aspects of overall renal function. Workshop
topics included solute fluxes through ion channels, cotransporters,
and metabolically-driven ion pumps; transport across fiber-matrix
and capillary membranes; coordinated transport by renal epithelia;
the urine concetrating mechanism; and intra-renal hemodynamic
control. This volume will be of interest to biological and
mathematical scientists who would like a view of recent
mathematical efforts to represent membrane transport and its role
in renal function.
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