Neuroimmune Circuits, Drugs of Abuse, and Infectious Diseases (Hardcover, 2001 ed.)

This volume focuses on the relationship between the nervous and the immune system with regard to the effects of drugs of abuse and infections, including infection caused by the immunodeficiency virus which causes AIDS, the number one health problem worldwide. Chapters focus on the brain-immune axis, detailing the effects of drugs of abuse. It is well known that recreational drugs of abuse such as morphine, cocaine, and marijuana, as well as other drugs, including the legal drugs alcohol and nicotine, are used by large numbers of individuals. Serious concerns have been raised about the consequences of using such drugs, especially in relation to their effects on normal physiological responses, including immune mechanisms. It is now widely recognized not only that many drugs of abuse have serious consequences on normal parameters of neurologic and neuroendocrine systems in general but also that effects on those systems, in turn, may affect indirectly immunity and also directly affect immune systems. Much data has now been accumulated showing that drugs of abuse markedly alter the immune response in human populations as well as in experimental animals, both in vivo and in vitro. Furthermore, studies on microbial infections have shown that many drugs of abuse are associated with increased susceptibility to infectious diseases, especially opportunistic intracellular microorganisms, including viruses such as HIV which causes AIDS. The mechanisms whereby drugs of abuse increase the likelihood of infections by opportunistic microorganisms in humans as well as in experimental animals are delineated. This volume will further the understanding of the impact of drugs of abuse on the brain-immuneaxis and its relationship to immunomodulation and infection, especially that caused by the AIDS virus.

General

Imprint:	Kluwer Academic / Plenum Publishers
Country of origin:	United States
Series:	Advances in Experimental Medicine and Biology, 493
Release date:	November 2001
First published:	2001
Editors:	Herman Friedman • Thomas W. Klein • John J. Madden
Dimensions:	234 x 156 x 18mm (L x W x T)
Format:	Hardcover
Pages:	274
Edition:	2001 ed.
ISBN-13:	978-0-306-46466-9
Categories:	Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN:	0-306-46466-7
Barcode:	9780306464669

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