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Taxus - The Genus Taxus (Paperback)
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Taxus - The Genus Taxus (Paperback)
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Taxol, originally derived from the North American Yew tree in 1971,
is well-known worldwide as a powerful anticancer agent.
Mechanistically, it has a unique microtubule stabilizing activity,
and was clinically developed as a therapeutic agent in the
treatment of breast and ovarian cancers at the National Cancer
Institute, Washington D.C., USA. In this volume, the authors
provide an authoritative account of the taxoids. it covers their
production and biosynthesis - from commercial cultivation to plant
tissue culture methods - describes taxoid chemistry, the analytical
methods for identifying their structure and the pharmacological and
pre-clinical aspects important in investigating their therapeutic
actions. It presents a thorough review of the scientific
literature, including data from scientists currently engaged in
taxoid research, and will be of significant value to researchers
and others who wish to gain a practical perspective on taxoid
research and development.
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