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Recollections of 45 Years in Research - From Protein Chemistry to Polymeric Drugs to the EPR Effect in Cancer Therapy (Paperback)
Loot Price: R1,215
Discovery Miles 12 150
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Recollections of 45 Years in Research - From Protein Chemistry to Polymeric Drugs to the EPR Effect in Cancer Therapy (Paperback)
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This book describes the lifelong research experience of a
scientist, from the beginning studies of protein chemistry to the
development of a protein drug. Also discussed herein include the
invention of the first polymer conjugate drug
poly(styrene-co-maleic acid (SMA) conjugated to NCS, GBP called
SMANCS. The author, having acquired knowledge of proteases and
inhibitors, pioneered investigations of microbial proteases in the
pathogenesis of bacterial infection. The author -s group, using a
polymer-conjugated enzyme, discovered an enormous burst in the
generation of superoxide anion radical during influenza virus
infection by the generation of xanthine oxidase, which was found to
be the major cause of the pathogenesis of this viral infection,
which progressed even after the virus was eradiated.
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