Proteomics for Drug Discovery - Methods and Protocols (Hardcover, 1st ed. 2017)

This book reflects the drug development community's interest in proteomics methods by providing researchers with the necessary knowledge for the implementation of a number of basic experimental and bioinformatics protocols in the drug discovery research laboratory. The focus of the collection is on select protocols and methodologies that address the analysis of post-translational modifications, targeted protein quantification, protein-protein, protein-lipid, or protein-ATP interactions, in silico lead identification, protein arrays, tissue and cell extract preparation, labeling, chemoproteomics, and drug efficacy assessment. Emphasis was placed not just on methods that describe large-scale protein analysis, but also on ones that are amenable to future implementation in a high-throughput format. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Proteomics for Drug Discovery: Methods and Protocols aims to provide a deep knowledge of the fundamentals of disease biology as well the means that were developed for probing the complex biological milieu.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Molecular Biology, 1647
Release date:	August 2017
First published:	2017
Editors:	Iulia M. Lazar • Maria Kontoyianni • Alexandru C. Lazar
Dimensions:	254 x 178mm (L x W)
Format:	Hardcover
Pages:	302
Edition:	1st ed. 2017
ISBN-13:	978-1-4939-7200-5
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General
LSN:	1-4939-7200-6
Barcode:	9781493972005

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