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Books > Professional & Technical > Agriculture & farming > Forestry & silviculture: practice & techniques
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The Endometrium - Hormonal Impacts (Paperback, Softcover reprint of the original 1st ed. 1981)
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The Endometrium - Hormonal Impacts (Paperback, Softcover reprint of the original 1st ed. 1981)
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Although the physiology of the menstrual cycle appears clear and
easily explained by a balance in the concentration of various sex
steroid hormones, numerous details of its mechanism are still
poorly understood and little is known about the relationship among
clinical events, plasma hormone concentrations, molecular impacts
on target tissues and their regulation. In the following chapters,
the authors have attempted to establish a correlation between
endometrial histology and well-understood physiologic events of the
menstrual cycle. They have provided up-to-date information on the
effects of various hormones and combinations of hormones on the
endometrium. The interdependence of endometrial morphology,
molecular biology, endocrinology and physiology, provides grounds
for a better understanding of the complex mechanism of the
menstrual cycle, and sheds some light on its pathophysiology. Such
an approach adds ariother dimension to interpretation of many
menstrual abnormalities and numerous aspects of infertility in
women with normal physiognomies and apparently regular menstrual
cycles. The pathologist must be aware of these new concepts since a
knowledge of functional changes reflected in hormone serum levels
and sex steroid receptor concentrations allows a mare detailed
analysis and a better interpretation of the structural features of
the endometrium. This information placed in the proper clinical
context can help the gynecologist provide optimal therapy. The
reader will find a valuable reference for a synthesis of clinical,
morphological, and biochemical data related to the menstrual cycle
and its aberrations.
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