In order to understand drug metabolism at its most fundamental
level, pharmaceutical scientists must be able to analyze drug
compound structure and predict possible metabolic pathways in order
to avoid the risk of adverse reactions that lead to the withdrawal
of a drug from the market. This title is a comprehensive guide for
recognizing the chemical underpinnings of drug metabolism. While
there are numerous resources available to medicinal chemists for
understanding drug structure, and to pharmacologists for discerning
drug metabolism from a biological standpoint, no resource currently
exists that links the chemical and biological aspects in language
accessible to both-making it challenging for both groups to fully
comprehend how a drug is metabolized, as well as the potential
effects of the metabolites. Drug Metabolism: Chemical and Enzymatic
Aspects provides extensive material to help understand drug
metabolism within a biological context, and for predicting and
mitigating adverse drug reactions.
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