A green chemical synthetic protocol has been developed for the
rapid parallel synthesis of a library of biologically potential
2-amino-4-arylthiazoles, employing water as a solvent under
microwave irradiation (MWI). This novel process yields the target
NCE's in very short time, good yield and purity. The judicious use
of water as green solvent is attractive and cost effective &
makes the process eco-friendly. Besides the general discussion on
the biology and synthesis of 2-aminothiazoles, a short review on
MWI and use of water as a green solvent is also included. The
target NCE's bear good antifungal and antibacterial potential.
General
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