Chronic Fatigue Syndrome (CFS) is now a recognized major and
international medical concern. Neglected for many years because of
its puzzling wide range of symptoms and inability to be "slotted"
into any single mainstream medical discipline, CFS has gained
government, academic, and public attention. In this innovative
book, Dr. Jay Goldstein provides a medical narrative of an
"evolving theory" of how the symptoms of CFS may develop through
dysfunction of numerous physiological pathways. He describes the
biologic basis of these assumptions, and, based on an analysis of
basic medical principles, leads the reader to logical conclusions.
In addition, Dr. Goldstein reveals a wealth of clinical experience
by describing successes and failures of various therapies and
discusses the reasons for the outcomes. Dr. Goldstein s private
practice is devoted to patients who fit the profile of a CFS
sufferer. As a result, his extensive clinical experience has given
him a unique hands-on perspective not readily available to most
researchers.Chronic Fatigue Syndromes: The Limbic Hypothesis
carefully reviews the extant research literature in each chapter.
Although Dr. Goldstein cautions that this model should be viewed
only as a PROMISING FOUNDATION for future research, no less than
six peer reviewers, all leading researchers and clinicians in the
CFS field, have endorsed the direction of Dr. Goldstein s bold
proposition. The breadth and scope of this book is perhaps best
summarized by Paul Cheney, MD, PhD, a national leader in the field:
"Despite its long history, the medical establishment with its great
advances in biotechnology has been largely unable to crack the
basic pathophysiology of the chronic fatigue syndrome. . . . Dr.
Goldstein s new book takes us to a place few people know well, and
describes a plausible mechanism of injury to the deep brain which
could explain every symptom seen in patients with] chronic fatigue
syndrome. . . . It is the unifying power of his hypothesis,
together with emerging scientific support for this view, that makes
this book an important one to read for both the patient with CFS,
as well as the practitioner and medical scientist who attempt to
understand it."
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