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Toxicology of the Kidney (Paperback, 3rd edition)
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Toxicology of the Kidney (Paperback, 3rd edition)
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The kidney plays a vital role in certain endocrine functions.
Abnormalities caused by toxic chemicals or other interventions can
have profound effects on these functions and consequently, on total
functions. Toxicology of the Kidney, Third Edition is updated to
reflect the latest research in this field and focuses on the
correlation between anatomy, biochemistry, and physiology of the
kidney. The text explains how these factors are related to concepts
of clinical nephrotoxicity and renal failure in humans, and how
animal models can be used to understand the mechanisms of human
renal disease. In addition to updating many of the key elements of
previous editions, such as in vitro models for studying renal
function and toxicity and classic nephrotoxicants, it also
incorporates cutting edge information on newly emerging areas of
renal research. These include mechanisms of cell injury, signaling
pathways, biomarkers of renal disease and the interface between
basic renal science and clinical outcomes. This book includes
current reviews of unpublished and recently published information
which allows it to serve as a concise compendium of many key topics
that will continue to play a central role in our understanding and
treatment of nephrotoxicity for decades to come.
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